Neuroimaging

Speech production in healthy aging

Sörös P, Bose A, Sokoloff LG, Graham SJ, Stuss DT. Age-related changes in the functional neuroanatomy of overt speech production. Neurobiol Aging. 2009 (in print). PubMed | PDF
Abstract
Alterations of existing neural networks during healthy aging, resulting in behavioral deficits and changes in brain activity, have been described for cognitive, motor, and sensory functions. To investigate [...]

Rapid auditory processing in healthy aging

Sörös P, Teismann IK, Manemann E, Lütkenhöner B. Auditory temporal processing in healthy aging: a magnetoencephalographic study. BMC Neuroscience 2009. PubMed | PDF
The findings of the present MEG study do not provide evidence for the hypothesis that auditory temporal processing, as measured by the decrement (short-term habituation) of the major auditory evoked component, the N1m [...]

Meta-analysis of swallowing-related brain function

Sörös P, Inamoto Y, Martin RE. Functional brain imaging of swallowing: An activation likelihood estimation meta-analysis. Hum Brain Mapp 2009. PubMed | PDF
This paper presents the first quantitative voxel-wise meta-analysis of swallowing-related brain function. Data analysis was performed with the activation likelihood estimation (ALE) approach, using the freely available software GingerALE.
Abstract
A quantitative, voxel-wise meta-analysis was [...]

Functional MRI of oropharyngeal air-pulse stimulation

Sörös P, Lalone E, Smith R, Stevens T, Theurer J, Menon R, Martin R. Functional MRI of oropharyngeal air-pulse stimulation. Neuroscience 2008, 153: 1300-1308. PubMed | PDF

Background: Although the posterior oral cavity and oropharynx play a major role in swallowing, their central representation is poorly understood.
Methods: High-field functional magnetic resonance imaging of the brain [...]

Dysphagia Research Society 2008

The following oral presentation, given at the Dysphagia Research Society 2008 in Charleston, SC, USA, presents a study on somatosensory processing of brief air-pulse stimuli. A more detailed description of this study can be found here.
Sörös P, Lalone E, Smith R, Stevens T, Theurer J, Menon R, Martin R. Functional MRI of oropharyngeal air-pulse stimulation. [...]

fMRI of vibrotactile processing

Sörös P, Marmurek J, Tam F, Baker N, Staines WR, Graham SJ. Functional MRI of working memory and selective attention in vibrotactile frequency discrimination. BMC Neuroscience 2007, 8:48. PubMed Abstract Reprint

Background. To characterise the neural correlates of intact vibrotactile working memory and attention, we conducted functional MRI in 12 healthy young adults. Participants [...]

Functional imaging of speech production

This is a presentation I gave at the Ontario Aphasia Interest Group Teleconference in December 2006. It summarizes the findings of my fMRI study on speech production in healthy younger adults (Neuroimage 2006;32(1):376-387). The presentation is available as Flash web presentation or as a pdf (6 MB).

The neurochemical basis of auditory processing

Sörös P, Michael N, Tollkötter M, Pfleiderer B. The neurochemical basis of human cortical auditory processing: Combining proton magnetic resonance spectroscopy and magnetoencephalography. BMC Biology 2006;4:25. PubMed Fulltext Reprint

Abstract
A combination of magnetoencephalography and proton magnetic resonance spectroscopy was used to correlate the electrophysiology of rapid auditory processing and the neurochemistry of [...]

Auditory processing in stroke

This study in Neurology asks if a complete infarction of the auditory cortex affects the magnetoencephalographic correlates of auditory processing in the contralateral, unaffected hemisphere. We found no evidence for changes in contralateral auditory processing, suggesting that the auditory system does not reorganize after a large unilateral infarction.
Sörös P, Dziewas R, Manemann E, Teismann IK, [...]

Posters for Human Brain Mapping 2006

Clustered fMRI of speech production.
This poster depicts the neural network involved in speech production as found in 9 young adults, based on my paper in Neuroimage.
Sörös P, Guttman Sokoloff L, Bose A, McIntosh AR, Graham SJ, Stuss DT. Clustered fMRI of speech production. Neuroimage 2006;31(Supplement 1):S113. Download

Age-related reorganization of the functional neuroanatomy [...]

Neural correlates of speech production

This fMRI study in Neuroimage investigates brain activation during the production of a vowel and consonant-vowel syllables in the magnet. For the reduction of speech-related artefacts, clustered image acquisition was performed. The study revealed the widespread neural circuitry involved in speech production.
Sörös P, Sokoloff LG, Bose A, McIntosh AR, Graham SJ, Stuss DT. Clustered functional [...]